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Clinical

Foreword

Beyond the invaluable dosage of serum creatinine, Clinical Chemistry continues to greatly contribute to the majority of decision-making processes encountered in Nephrology. This is evident for the so-called “Chronic Kidney Disease-Mineral and Bone Disorder” for which, both diagnosis and prognosis largely benefit from numerous informative markers provided by the Biochemist. This is even more obvious with the continuous development of new biomarkers in the field of Acute Kidney Injury – the Quest for the kidney BNP – and of Transplantation as well – the Quest for dysfunction prediction –.

The different chapters assembled in this ebook under the direction of Dr Pierre DELANAYE cover the main biological aspects of “modern” Nephrology. Most of them are precious tools already available for the Clinicians.

We have no doubt that the Nephrology community will welcome this ebook and will acknowledge the helpful hand, the biochemist keeps offering us.

Rossini C. Botev, MD, FASN
Department of Nephrology
HPMG
Honolulu, HA
USA

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France

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Description

Introduction to Clinical Chemistry presents the physiological background for a number of investigations. It discusses the principles and analytical techniques in clinical chemistry. It addresses the basic understanding of chemical pathology. Some of the topics covered in the book are basic principles of metabolic chemistry; disorders of carbohydrate metabolism; nitrogen metabolism; inborn errors of metabolism; chemical endocrinology; assessment of hormonal function; liver function; the formation of bile; and the synthesis and metabolism of amino acids and protein. The storage of carbohydrates and removal of toxic substances from the body are covered. The assessment of liver function is discussed. The text describes the renal function and acid-base metabolism. A study of the renal tubular reabsorption and excretion is presented. A chapter is devoted to the hydrogen ion concentration and analytical techniques in potentiometric determination. Another section focuses on the measurement of osmolality. The book can provide useful information to scientists, physicists, doctors, students, and researchers.


Preface
1 Basic Principles of Metabolic Biochemistry
Carbohydrate Metabolism
Lipid Metabolism
Nitrogen Metabolism
2 Chemical Endocrinology
Introduction
The Pituitary
The Thyroid
The Parathyroid Glands
The Pancreas
The Adrenal (Suprarenal) Glands
The Testes
The Ovaries
Gastrointestinal Hormones
Assessment of Hormonal Function
3 Liver Function
Anatomy
Function
Assessment of Liver Function
4 Renal Function and Acid-Base Metabolism
Anatomy
Function
Assessment of Renal Function
5 Analytical Techniques and Clinical Chemistry
Potentiometric Determination
Spectroscopy
Spectrophotometry
The Measurement of Osmolality
Immunological Techniques
Chromatographie Separation
Protein Electrophoresis
Radioisotope Technique
6 Basic Principles of Laboratory Investigations
Bilirubin
Calcium
Cholesterol
Creatine and Creatinine
Drugs and Poisons
Enzyme Determination
Glucose
Hormones
Phosphate
Proteins
Renal Calculi
Triglycerides
Urea
7 Management in Clinical Chemistry
The Maintenance of Equipment And Supplies
Ergonomics
Safety
Confidence in Chemical Analysis
Work Simplification and Mechanization
The Introduction of New Methods
References
Index

Details

No. of pages:
180
Language:
English
Copyright:
© Butterworth-Heinemann 1987
Published:
11th August 1987
Imprint:
Butterworth-Heinemann
eBook ISBN:
9781483182599

Clinical Chemistry Book Pdf

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